Julian Draxler, Idrissa Gueye and Kylian Mbappe added another three in the second half while Angers pulled one back in the 52nd minute.
Colombia will face Venezuela in Barranquilla on Friday and Chile in Santiago four days later.
Alessandro Florenzi, the only new face at the Parc des Princes this summer, scored his first goal for the club to open the scoring seven minutes into the game before Neymar hit twice in the 36th and 47th minute to make it 3-0.
In the first competition day of Wuhan Zall, team of the hardest-hit city, fans are gathering with strong passion. For some, the fighting sprits of the matches may encourage them to overcome the stressful times.
"Everyone on the team has to contribute in some way," she noted.
The Argentinian bested Nadal in the Rome Masters quarter-finals last month for his first win against the world number two.
Shortly after the second, Xinjiang used another 13-2 spurt to put the game out of sight as Wuhan's shooting froze up.
On the Shanghai side, Zhou Yuyan had 11 points, and Han Xu bagged 10.
Colombia will host Venezuela in Barranquilla on October 9 before facing Chile in Santiago four days later.
"Adam has had an unbelievable couple of years with the club and has had a huge influence on our squad," he said.
Earlier on Friday, Jiangsu defeated Shanghai 3-0 (25-17, 25-20, 26-24) in the third-place match.